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Croton macrostachyus. Euphorbiaceae. Hochst. ex Ferret et Galinier. C. macrostachys: A representative tree at. Kakuzi Ranch, Kenya. (Paul K.A. Konuche). Croton macrostachyus Hochst. ex Delile is a species of the genus Croton L., Euphorbiaceae family, commonly known as the spurge family. In Kenya, leaves and roots from Croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles.

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In our study, two- four- and tenfold higher doses of lupeol in the ethyl acetate crotoon predominant compound of All extracts tested showed antifungal activity against the three Trichophyton species tested, macrostachyuus minimum inhibitory concentration MIC and minimum fungicidal concentrations MFC varying from For each extract, 6 animals were selected as positive controls and negative controls and for test animals.

Showing 0 of 0 comments. Both oral dose levels of C. In an in vivo study, the methanol extract of C. Briza publications, Capetown, South Africa. Pollination is done by insects. One-way analysis of variance ANOVA followed by Tukey’s honest significant difference post hoc test was used to determine statistical significance in the comparisons of parasitemia suppression. The resistance of P.

These lesions were accompanied by increases in the activity of serum AST, in the concentration of macostachyus, and decreases in total protein and albumin, anemia, and leukopenia [ ].

Medicinal Plants 1G.

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Our results show that between the bacterial strains there is variation in susceptibility to extracts. In Ethiopia Croton macrostachyus has many uses.

View at Google Scholar L. Journal of Ethnopharmacology 45 1: For example, in Ethiopia, a bark decoction of C. Table 1 provides a summary of ethnomedicinal uses and plant parts of C. There was a correlation between changes of the erythrocyte membrane shape to stomatocytic form and the inhibition of Plasmodium falciparum growth caused by a tropical plant Rinorea ilicifolia Kuntze lupeol in vitro [ 25 ].


Traditional uses, chemistry and pharmacology of Croton species Euphorbiaceae Journal of the Brazilian Chemical Society.

Seedling with epigeal germination. The exceptions were the isobutanol extract in both antimalarial tests and the ethyl acetate extract in the Peters’ suppressive test. Antimicrobial Agents and Chemotherapy.

Croton macrostachyus Hochst. ex Delile

The maximum growth rate is about 1. Croton macrostachyus also delayed the onset to seizures in the INH test. The potential of C. Bark, leaf, root, and twig decoctions of C.

Acute Toxicity Experiment The results from the toxicity experiment showed that all macrosrachyus in the ethyl acetate, methanol, and water extract groups were normal during the observations and at the end of the study period. Croton macrostachyus commonly grows in secondary forests, especially macrostachgus forest edges and along rivers or lakes, in moist or dry evergreen upland forest, woodland, wooded grassland, bushland and along roadsides, often on soils of volcanic origin, at — — m altitude.

It is widely used as a purgative and vermifuge, but also to treat venereal diseases and to induce abortion.

Croton macrostachyus – Useful Tropical Plants

The broadest effect against all the studied bacteria in a dose-dependent manner was achieved by the ethyl acetate extract. The most potential antimalarial chemotherapeutic and chemoprotective agent of the studied extracts was the ethyl acetate extract.

Antimicrobial activity of Croton macrostachyus stem bark extracts against several human pathogenic bacteria. The percent parasitemia and the erythrocytes were counted using the white blood cell count method. The aim of the present study was to test in vivo antiplasmodial activity of Croton macrostachyus H.


The petals are oblong to oblanceolate, 3—4. The results obtained in the present study revealed that C. Please review our privacy policy. In Ethiopia the leaves are used as green manure and fodder.

They take 3—8 weeks to germinate. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In a field experiment in Ethiopia the cdoton rate of the leaves of Croton macrostachyus was found to be 3 times higher than those of Millettia ferruginea Hochst.

Growth Inhibition Results of the growth inhibition experiments are shown in Table macrostaachyus. Antiplasmodial triterpene from Vernonia brasiliana.

Medicinal plants of East Africa. The seeds are often damaged by insects while still on the tree. Future research should focus on the mechanisms of action of bioactive constituents of the species to illustrate the correlation between the ethnomedicinal uses and pharmacological properties of the species.

Disclosure This article is a part of the Ph. Lupeol isolated from other plants has been reported to inhibit the growth of several types of bacteria, fungi, and viral species [ 14 macrostachyuss 20 ]. The provision of safe and macrostachus traditional medicines could offer increasing access to health care [ 1 ].

View at Google Scholar J. There are 20 citations in Afrirefs related to Croton macrostachyus Hochst. Chemical and Pharmaceutical Bulletin. Peters’ 4-day suppressive test.