L O A D I N G
blog banner

CAFEINA EN APNEA DEL PREMATURO PDF

Intoxicación por cafeína en un recien nacido prematuro Caffeine citrate is used as first-line therapy in neonates to treat or prevent apnea of prematurity. This is not the most recent version of this Review. Please comment on the current version. view the current version 20 Jan Si su bebé no tenía apnea ni bradicardia en UCIN o si la frecuencia o puede recibir medicamentos (teofilina o cafeína) para disminuir los episodios. Los bebés recién nacidos prematuros corren el riesgo de hernias, que.

Author: Gardagami Mautaxe
Country: Cuba
Language: English (Spanish)
Genre: Sex
Published (Last): 7 April 2010
Pages: 391
PDF File Size: 4.97 Mb
ePub File Size: 15.41 Mb
ISBN: 152-7-84949-671-5
Downloads: 23703
Price: Free* [*Free Regsitration Required]
Uploader: Fesar

Simultaneous high-performance liquid chromatographic determination of caffeine and theophylline for routine drug monitoring in human plasma. In our study, detected levels of caffeine in umbilical cord blood did not decrease occurrence of apnea of prematurity, but it had a borderline effect delaying its occurrence, suggesting that even premauro low level of caffeine in umbilical cord blood might delay occurrence of apnea spells. This study aimed at determining the influence of presence of caffeine in umbilical cateina blood on the incidence and time of occurrence of apnea of prematurity in the first days of life.

Níveis plasmáticos de cafeína no cordão umbilical e apneia da prematuridade

Prwmaturo patients with diagnosis of sepsis were submitted to lumbar puncture. A rapid HPLC method for monitoring plasma levels of caffeine and theophylline using solid eb extraction columns. Long-term effects of caffeine therapy for apnea of prematurity. Concentrations of caffeine and paraxanthine in saliva were measured in pregnant women in the United Kingdom levels of caffeine in plasma and saliva are strongly correlatedand the mean concentration of caffeine was 0.

Umbilical blood was collected in preterm neonates; 21 of them were subsequently excluded seven for presenting apnea once with no need for treatment, five for remaining in mechanical ventilation until the fourth day eel life, three for PIVH degrees 3 and 4, one for exchange transfusion, five for methylxantine prior to extubationand three were lost two due to insufficient sampled quantity for caffeine dosage and one due to family request.

Apneas del prematuro pdf. Preterm infants with birth weight of to 1, g treated with caffeine during the first 10 days have caveina reduced rate of bronchopulmonary dysplasia, and present a better neurodevelopmental outcome at 18 to 21 months than a control group. Schreiber-Deturmeny E, Bruguerolle B.

  ANTONN BLAHOVEC ELEKTROTECHNIKA 1 PDF

A simple liquid chromatographic method applied to determine caffeine in plasma and tissues. Eighty-seven newborns with and 40 without detectable caffeine in umbilical cord blood were studied. Un recien nacido prematuro es aquel que nace antes de completar la semana 37 de ges-tacion2, feina no solo mejora las apnea del cafenia El diagnostico de apnea del prematuro debe plantearse despues de excluir infecciones, inestabilidad termica, hemorragia intracraneana http: Logistic regression analysis showed that none of those variables was associated with presence of caffeine in umbilical cord blood.

Transplacentally acquired caffeine and the occurrence of apnea, bradycardia, and periodic breathing in preterm infants: Neonates were divided into detectable and undetectable caffeine in umbilical cord blood. Sintomas de apnea del sueno en los bebes. Apnea is associated with neurodevelopmental impairment in very low birth weight infants. No apnes was observed in occurrence of apnea between both groups, but diagnosis of apnea was obtained through pneumography, which was performed only after clinical stability and in patients that did not require ventilatory support or oxygen therapy, thus excluding patients with serious conditions.

Acknowledgements We thank Vania Naomi Eh for her assistance with the statistical analysis, and Carmen Pilla, BSc, for her assistance with the caffeine ddel analysis.

Some studies quantified maternal use of caffeine during pregnancy. Silveira II ;Renato S. The role of maternal consumption of caffeine and occurrence of apnea in preterm neonates have aroused general interest.

Determination of caffeine, theophylline and theobromine in serum and saliva using high performance liquid cafsina. En la apnea, la respiracion cesa temporalmente y luego regresa a la normalidad. En que consiste la apnea del prematuro? There was no association between occurrence of apnea spells and presence of caffeine in umbilical cord blood. Table 1 shows the group characteristics. Carlos Gomes, cj. None of them showed significance Table 3.

Caffeine is probably the most frequently drug taken in the world, consumed prematro people of all ages.

Introduction Treatment premaaturo apnea of prematurity includes pharmacological approach with caffeine, a powerful stimulant of the central nervous system that reduces occurrence of neonatal apnea, promotes consolidation of a regular pattern of breathing and increases alveolar ventilation.

Results Umbilical blood was collected in preterm neonates; 21 of them were subsequently excluded seven for presenting apnea once with no need for treatment, five for remaining in mechanical ventilation until the fourth day of life, three for PIVH degrees 3 and 4, one for exchange transfusion, five for methylxantine prior to extubationand three were lost two due to insufficient sampled quantity for caffeine dosage and one due to family request.

  EUROTHERM 5100V PDF

Como citar este artigo. Definicion Apnea significa interrupcion de la respiracion. Neonatal withdrawal symptoms after chronic maternal ingestion of caffeine.

Treatment of apnea of prematurity includes pharmacological approach with caffeine, a powerful stimulant of the central nervous system that reduces occurrence of neonatal apnea, promotes consolidation of a regular pattern of breathing and increases alveolar ventilation. This study showed that neonates with detectable and undetectable levels of caffeine in umbilical cord blood had similar occurrence of apnea, and rn the neonates who presented apnea, occurrence was later in preterm neonates with detectable levels of caffeine.

Diagnosis of apnea was performed through patient’s monitoring, and it was defined as interruption of breathing for 20 s or more, or interruption of shorter duration if followed by cyanosis, hypotension or bradyarrhythmia.

There was a problem providing the content you requested

Simultaneous determination of caffeine and its primary demethylated metabolites in human plasma by high-performance liquid chromatography. The method used in the gestational de assessment was preferably the obstetric gestational age obtained through ultrasonography in the first weeks of fetal life or, if such data were unavailable, the date of most recent menstruation confirmed through clinical exam of the neonate.

Consequences of in utero exposure on respiratory output in normoxic and hypoxic conditions and related changes of Fos expression: Manuscript submitted Oct 20accepted for publication Jan 21 The simultaneous determination of theophylline, theobromine and caffeine in plasma by high performance liquid chromatography.

Patients in group 2 had a statistically significant lower gestational age, and required more respiratory support CPAP and mechanical ventilation just after birth than those in group 1. For the diagnosis of meningitis, those with abnormal cerebrospinal fluid and positive culture were considered. As caffeine is a substance that crosses the placental barrier, it could have an intrauterine stimulation of the fetus’s respiratory center.